麻醉和手术对肾功能的影响9-20

3.0 小沃沃 2026-02-16 999+ 1.04MB 25 页

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EFFECTS OF

ANESTHESIA &

SURGERY ON RENAL

FUNCTION

EFFECTS OF ANESTHESIA

ON RENAL FUNCTION

•direct effects

indirect effects

•important variables

–surgical procedure

–fluid administration

–preexisting cardiac function

–preexisting renal function

EFFECTS OF ANESTHESIA

ON RENAL FUNCTION

(1) Reversible ↓ in RBF, GFR, urinary flow, and Na+ excretion

occur during both RA and GA.

(2) Changes are generally less marked during RA.

(3) Most of these changes are indirect and are mediated by

autonomic and hormonal influences.

(4) These effects can be at least partially overcome by

maintenance of an adequate intravascular volume and a

normal blood pressure.

(5) Only a few anesthetics (methoxyflurane and, theoretically,

enflurane and sevoflurane) in high doses can cause

specific renal toxicity.

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EFFECTSOFEFFECTSOFANESTHESIA&ANESTHESIA&SURGERYONRENALSURGERYONRENALFUNCTIONFUNCTIONEFFECTSOFANESTHESIAONRENALFUNCTION•directeffectsindirecteffects•importantvariables–surgicalprocedure–fluidadministration–preexistingcardiacfunction–preexistingrenalfunctionEFFECTSOFANESTHESIAONRENALFUNCTION(1)Reversi...

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麻醉和手术对肾功能的影响9-20

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